OPN1SW anticorps (N-Term)

N° du produit ABIN7540578

N° du produit (Fournisseur): 600-101-mp7

L’anticorps Chèvre Polyclonal anti-OPN1SW a été validé pour ELISA et IHC. Il convient pour détecter OPN1SW dans des échantillons de Souris. Il y a 2+ publications disponibles.

Aperçu rapide pour OPN1SW anticorps (N-Term) (ABIN7540578)

Antigène: OPN1SW (Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW))

Reactivité: Souris

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp OPN1SW est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-OPN1SW anticorps

Épitope: N-Term

N° du produit (Fournisseur): 600-101-mp7

Fournisseur: Rockland

Fonction: S Opsin Antibody

Réactivité croisée (Details): This affinity purified antibody is directed against mouse S Ospin.

Purification: The product was affinity purified from monospecific antiserum by immunoaffinity purification.

Stérilité: Sterile filtered

Immunogène: Anti-S Opsin antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to a N-terminal portion of mouse S Opsin conjugated to Keyhole Limpet Hemocyanin (KLH).

Isotype: IgG

Information d'application

Indications d'application:

ELISA_Dilution: 1:10,000 - 1:50,000

Immunohistochemistry_Dilution: 1:100

Commentaires:

Suggested Applications:

Suggested_Applications: IF

Other_Performance_Data: The 1:100 H1-20 provides optimal staining with staining of structures in multiple layers. These layers have been shown to express S-opsin in the cited reference. For staining only in the outer segment layer, the 1:200 and 1:300 H2-20 appears to be ideal.

Anti-S Ospin Antibody has been tested in ELISA and IHC.  Expect a band at ~39kDa in western blot using appropriate tissues and lysates.  Positive control used: Mouse eye tissue in Immunohistochemistry.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Références pour anticorps anti-OPN1SW (ABIN7540578)

Gupta, Młynarski, Sumser, Symonova, Svatoň, Joesch: "Panoramic visual statistics shape retina-wide organization of receptive fields." dans: Nature neuroscience, Vol. 26, Issue 4, pp. 606-614, (2023) (PubMed).

Simons, Smith, Dengler-Crish, Crish: "Retinal ganglion cell loss and gliosis in the retinofugal projection following intravitreal exposure to amyloid-beta." dans: Neurobiology of disease, Vol. 147, pp. 105146, (2021) (PubMed).

Détails sur OPN1SW

Antigène: OPN1SW (Opsin 1 (Cone Pigments), Short-Wave-Sensitive (OPN1SW))

Autre désignation: Opn1sw

Sujet: Goat Anti-Short-wave-sensitive opsin 1 Antibody, S opsin, Blue cone photoreceptor pigment, Blue-sensitive opsin, BOP, Short wavelength-sensitive cone opsin, Bcp, Opn1sw,Short-wave-sensitive opsin 1 belongs to the G-protein coupled receptor 1 family, opsin subfamily. It encodes the blue cone pigment gene which is one of three types of cone photoreceptors responsible for normal color vision. Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. Required for the maintenance of cone outer segment organization in the ventral retina, but not essential for the maintenance of functioning cone photoreceptors. Involved in ensuring correct abundance and localization of retinal membrane proteins. May increase spectral sensitivity in dim light. Defects in this gene are the cause of tritan color blindness (tritanopia). Affected individuals lack blue and yellow sensory mechanisms while retaining those for red and green. Defective blue vision is characteristic. Anti-S Ospin Antibody is useful for researchers interested in Color Blindness, Metabolism of fat-soluble vitamins, and Peptide ligand-binding receptors.

ID gène: 12057

NCBI Accession: NP_031564

UniProt: P51491