SLC40A1 anticorps (Internal Region)

N° du produit ABIN7540602

N° du produit (Fournisseur): 600-401-mg1s

L’anticorps anti-SLC40A1 Polyclonal Lapin est utilisé pour la détection de SLC40A1 dans des échantillons de Humain. Il a été validé pour WB, ELISA, IF et FM.

Aperçu rapide pour SLC40A1 anticorps (Internal Region) (ABIN7540602)

Antigène: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC40A1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Fluorescence Microscopy (FM)

Détail du produit anti-SLC40A1 anticorps

Épitope: Internal Region

N° du produit (Fournisseur): 600-401-mg1s

Fournisseur: Rockland

Fonction: SLC40A1 Antibody

Réactivité croisée (Details): This affinity purified antibody is directed against human SLC40A1.

Purification: The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Stérilité: Sterile filtered

Immunogène: Anti-SLC40A1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of human SLC40A1 conjugated to Keyhole Limpet Hemocyanin (KLH).

Isotype: IgG

Information d'application

Indications d'application:

ELISA_Dilution: 1:10,000 - 1:50,000

IF_Microscopy_Dilution: 15 μg/mL

Western_Blot_Dilution: 10 μg/mL

Commentaires:

Anti-SLC40A1 Antibody has been tested in ELISA, WB, and IF.  Expect a band at ~62.5kDa in western blot using appropriate lysates.  Positive control used: Caco-2 lysate in Western Blot and Hep-G2 in Immunofluorescence.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

Date de péremption: 12 months

Détails sur SLC40A1

Antigène: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Autre désignation: SLC40A1

Sujet: Rabbit Anti-SLC40A1 Antibody, Solute Carrier Family 40 Member 1, Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 3, Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1, SLC11A3, IREG1, FPN1, Iron-Regulated Transporter 1, Iron Regulated Gene 1, Ferroportin-1, Ferroportin 1, MSTP079, MST079, HFE4, MTP1, SLC40A1 (Solute Carrier Family 40 Member 1) may be involved in iron export from duodenal epithelial cell and in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).  Defects in this gene are a cause of hemochromatosis type 4 (HFE4). Diseases associated with SLC40A1 include Hemochromatosis Type 4 and Type 1.  Anti-SLC40A1 Antibody is useful for researchers interested in mineral absorption, insulin receptor recycling, and transmembrane transporter activity.

ID gène: 30061

NCBI Accession: NP_055400

UniProt: Q9NP59

Pathways: Transition Metal Ion Homeostasis