SARS-CoV-2 Spike anticorps (RBD)

N° du produit ABIN7540678

N° du produit (Fournisseur): 600-401-ms8s

Cet anticorps anti-SARS-CoV-2 Spike est un anticorps Lapin Polyclonal détectant SARS-CoV-2 Spike dans ELISA, IF et FM. Adapté pour SARS Coronavirus-2 (SARS-CoV-2). Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour SARS-CoV-2 Spike anticorps (RBD) (ABIN7540678)

Antigène: SARS-CoV-2 Spike

Reactivité: SARS Coronavirus-2 (SARS-CoV-2)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SARS-CoV-2 Spike est non-conjugé

Application: ELISA, Immunofluorescence (IF), Fluorescence Microscopy (FM)

Détail du produit anti-SARS-CoV-2 Spike anticorps

Épitope: RBD

N° du produit (Fournisseur): 600-401-ms8s

Fournisseur: Rockland

Fonction: SARS-CoV-2 Spike Protein (RBD) Antibody

Réactivité croisée (Details): Anti-SARS-CoV-2 Spike affinity purified antibody is directed against SARS Coronavirus 2 Spike protein.

Purification: The product was purified from monospecific antiserum by immunoaffinity chromatography over SARS CoV-2 Spike resin.

Stérilité: Sterile filtered

Immunogène: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of the SARS Coronavirus Spike Protein within the Receptor Binding Domain (RBD).

Isotype: IgG

Information d'application

Indications d'application:

ELISA_Dilution: 1:150,000 - 1:450,000

IF_Microscopy_Dilution: 1:1000

Commentaires:

Suggested Applications: Other
Anti-SARS-CoV-2 Spike protein purified antibody has been tested for use in ELISA and IF. This antibody shows reactivity to recombinant SARS COV-2, S1 subunit protein and recombinant SARS COV-2 whole spike protein.  Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

Date de péremption: 12 months

Références pour anticorps anti-SARS-CoV-2 Spike (ABIN7540678)

Kaleta, Kern, Hong, Hölzer, Kochs, Beer, Schnepf, Schwemmle, Bollen, Kolb, Huber, Ulferts, Weigang, Dudas, Wittig, Jaki, Padane, Lagare, Salou, Ozer, Nnaemeka, Odoom, Rutayisire, Benkahla, Akoua-Koffi, Ouedraogo, Simon-Lorière, Enouf, Kröger, Calvignac-Sp: "Antibody escape and global spread of SARS-CoV-2 lineage A.27." dans: Nature communications, Vol. 13, Issue 1, pp. 1152, (2022) (PubMed).

Weigang, Fuchs, Zimmer, Schnepf, Kern, Beer, Luxenburger, Ankerhold, Falcone, Kemming, Hofmann, Thimme, Neumann-Haefelin, Ulferts, Grosse, Hornuss, Tanriver, Rieg, Wagner, Huzly, Schwemmle, Panning, Kochs: "Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants." dans: Nature communications, Vol. 12, Issue 1, pp. 6405, (2021) (PubMed).

Wang, Wang, Gupta, Morrissey, Naik, Singamaneni: "Enhancing the Stability of COVID-19 Serological Assay through Metal-Organic Framework Encapsulation." dans: Advanced healthcare materials, Vol. 10, Issue 18, pp. e2100410, (2021) (PubMed).

Détails sur SARS-CoV-2 Spike

Antigène: SARS-CoV-2 Spike

Autre désignation: SARS-CoV-2 Spike Protein

Sujet: Rabbit anti-SARS CoV 2 Spike Protein Receptor Binding Domain Antibody, Spike glycoprotein antibody, SARS CoV2 antibody, 2019-nCoV, COVID-19, S glycoprotein, Severe acute respiratory syndrome antibody, Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2),SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) the virus that causes the disease COVID-19, is related to SARS-CoV, MERS-CoV, and other betacoronaviruses (HKU1, NL63, OC43 and 229E). SARS-CoV-2 is an enveloped positive strand RNA virus that consists of several structural proteins including spike (S) protein, envelope (E) protein, membrane (M) protein and nucleocapsid (N) protein, and other non-structural proteins (NSPs). Spike proteins located on the surface of the virus, have a high affinity for binding to human receptor ACE2 (angiotensin-converting enzyme 2) within respiratory epithelial which serves as an entry mechanism for infection. As such, the S protein may be vital to blocking viral infection and vaccine development. Anti-SARS-CoV-2 Spike Protein Antibody is useful for researchers interested in diagnostics, vaccines, and viral research.

UniProt: P0DTC2