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Recombinant TNF alpha (Infliximab Biosimilar) anticorps

L’anticorps Souris Chimeric anti-TNF alpha (Infliximab Biosimilar) a été validé pour FACS, in vivo et ELISA. Il convient pour détecter TNF alpha (Infliximab Biosimilar) dans des échantillons de Humain.
N° du produit ABIN7542939

Aperçu rapide pour Recombinant TNF alpha (Infliximab Biosimilar) anticorps (ABIN7542939)

Antigène

TNF alpha (Infliximab Biosimilar)

Type d'anticorp

Recombinant Antibody

Reactivité

Humain

Hôte

  • 2
  • 1
  • 1
  • 1
Souris

Clonalité

  • 3
  • 2
Chimeric

Conjugué

  • 5
Cet anticorp TNF alpha (Infliximab Biosimilar) est non-conjugé

Application

  • 3
  • 3
  • 3
  • 1
Flow Cytometry (FACS), In vivo Studies (in vivo), ELISA

Clone

CA2
  • Fonction

    Anti-TNF alpha [cA2 (Infliximab)], Mouse IgG2a, kappa

    Specificité

    Binds to soluble and transmembrane forms of TNF-alpha and neutralizes its biological activity. Does not bind to TNF-beta.

    Attributs du produit

    Original Species of Ab: Human

    Original Format of Ab: IgG1

    Purification

    Protein A affinity purified

    Immunogène

    Purified recombinant human TNF (rTNF).

    Isotype

    IgG2a kappa
  • Indications d'application

    This antibody can be used to detect and neutralize human TNF alpha. Unlike Adalimumab (Ab00718), Infliximab does not bind to mouse TNF alpha (Arnoult 2017, PMID: 28584008).

    Commentaires

    This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    TNF alpha (Infliximab Biosimilar)

    Classe de substances

    Biosimilar

    Sujet

    TNF-α, TNFα, TNFSF, Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, TNFa

    UniProt

    P01375
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