Recombinant TNF alpha (Infliximab Biosimilar) anticorps
Aperçu rapide pour Recombinant TNF alpha (Infliximab Biosimilar) anticorps (ABIN7542939)
Antigène
Type d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Anti-TNF alpha [cA2 (Infliximab)], Mouse IgG2a, kappa
-
Specificité
- Binds to soluble and transmembrane forms of TNF-alpha and neutralizes its biological activity. Does not bind to TNF-beta.
-
Attributs du produit
-
Original Species of Ab: Human
Original Format of Ab: IgG1
-
Purification
- Protein A affinity purified
-
Immunogène
- Purified recombinant human TNF (rTNF).
-
Isotype
- IgG2a kappa
-
-
-
-
Indications d'application
- This antibody can be used to detect and neutralize human TNF alpha. Unlike Adalimumab (Ab00718), Infliximab does not bind to mouse TNF alpha (Arnoult 2017, PMID: 28584008).
-
Commentaires
-
This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % Proclin 300.
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
-
- TNF alpha (Infliximab Biosimilar)
-
Classe de substances
- Biosimilar
-
Sujet
- TNF-α, TNFα, TNFSF, Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, TNFa
-
UniProt
- P01375
Antigène
-