Recombinant ITGAL (Efalizumab Biosimilar) anticorps
Aperçu rapide pour Recombinant ITGAL (Efalizumab Biosimilar) anticorps (ABIN7542963)
Antigène
Type d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-CD11a [hu1124 (Efalizumab)], Mouse IgG2a, kappa
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Specificité
- Binds to human LFA-1.
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Attributs du produit
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Original Species of Ab: Human
Original Format of Ab: IgG1
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Purification
- Protein A affinity purified
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Immunogène
- Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.
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Isotype
- IgG2a kappa
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Indications d'application
- Efalizumab binds to the LFA-1 alpha I domain blocking the ICAM-1 binding site via steric hindrance.
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Commentaires
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This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- ITGAL (Efalizumab Biosimilar)
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Classe de substances
- Biosimilar
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Sujet
- LFA-1, integrin alpha L
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UniProt
- P20701
Antigène
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