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Recombinant CD45RC anticorps

Cet anticorps anti-CD45RC est un anticorps Lapin Chimeric détectant CD45RC dans FACS, IP et IHC. Adapté pour Rat.
N° du produit ABIN7543009

Aperçu rapide pour Recombinant CD45RC anticorps (ABIN7543009)

Antigène

Voir toutes CD45RC Anticorps
CD45RC

Type d'anticorp

Recombinant Antibody

Reactivité

  • 19
  • 10
  • 3
  • 2
Rat

Hôte

  • 19
  • 15
Lapin

Clonalité

  • 34
Chimeric

Conjugué

  • 15
  • 6
  • 6
  • 6
  • 1
Cet anticorp CD45RC est non-conjugé

Application

  • 33
  • 9
  • 5
  • 4
  • 4
  • 2
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Clone

OX-22
  • Fonction

    Anti-CD45RC [OX-22], Rabbit IgG, kappa

    Specificité

    OX-22 binds specifically to the high molecular weight form of the leucocyte common antigen, CD45RC. OX-22 and OX-31 compete for binding but do not compete with OX-32. The antigen is expresssed on the surface of B cells, around half of bone marrow cells, all CD8+ve T cells, and is able to differentiate between CD4+CD45RChigh (Th1-like) and CD4+CD45RClow (Th2-like) cell types. CD45 extracellular domain is able to interact with a number of different proteins including CD4, TCR, CD2, Thy-1 and CD26. CD45 is important for signalling throguh the T cell receptor and in the selection of T and B lymphocytes.

    Attributs du produit

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    Purification

    Protein A affinity purified

    Immunogène

    OX-22 was prepared by immunizing BALB/c mice with phytohemagglutinin-activated rat lymph node cells.

    Isotype

    IgG kappa
  • Indications d'application

    OX-20 can be used for both FC and IHC (paraffin/frozen) studies. It can also be used to purify proteins by affinty-purification (Woolett et al. Eur J Immunol. 1985 Feb,15(2):168-73).

    Commentaires

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    CD45RC

    Autre désignation

    CD45RC

    Sujet

    L-CA, Receptor-type tyrosine-protein phosphatase C, leukocyte common antigen, T200, CD45, OX22, MRC OX22, MRC OX-22, CD45 R

    UniProt

    P04157
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