Recombinant CD200R1 anticorps

N° du produit ABIN7543014

L’anticorps Souris Monoclonal anti-CD200R1 a été validé pour WB, FACS, IP, IHC (fro) et BR. Il convient pour détecter CD200R1 dans des échantillons de Rat.

Aperçu rapide pour Recombinant CD200R1 anticorps (ABIN7543014)

Antigène: CD200R1 (CD200 Receptor 1 (CD200R1))

Type d'anticorp: Recombinant Antibody

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD200R1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR)

Clone: OX-102

Détail du produit anti-CD200R1 anticorps

Fonction: Anti-CD200R [OX-102], Mouse IgG1, kappa

Specificité: This antibody is specific for CD200R (OX2R), a cell-surface receptor for OX2 restricted to cells of the myeloid lineage, macrophages isolated from the peritoneal cavity, lung, spleen, and leukocyte dendritic cells are highly positive in OX102 mAb staining tests.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: 6 week-old male BALB/c mice immunized six times with either 0.1-0.25 mg of a crude Tween-40 membrane fraction solubilized from rat (PVG) thioglycollate-elicited peritoneal cells or unlysed whole cells.

Isotype: IgG1 kappa

Information d'application

Indications d'application: This antibody binds the rat OX2 receptor, and thus can be used to stain rat resident peritoneal cells (RPCs), as well as macrophages from the lung, spleen and brain, and leukocyte dendritic cells (Wright, 2000). In addition, this antibody can be used to block the binding of OX2-coated beads to rOX2R on rat macrophages and to human kidney endothelial cells transfected with rOX2R cDNA. This antibody can also be used to purify the rOX2R antigen by immunoprecipitation from rat splenic lysates. Finally, the use of this antibody to block the OX2-OX2R interaction in rats with experimental allergic encephalomyelitis exacerbates the disease, and indicates a role for the OX2-OX2R interaction in the regulation of macrophage/microglia activity in vivo.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD200R1

Antigène: CD200R1 (CD200 Receptor 1 (CD200R1))

Autre désignation: CD200R

Sujet: OX2R, CD200, OX2

UniProt: Q9ES58