Recombinant CD48 anticorps (Extracellular Domain)
Aperçu rapide pour Recombinant CD48 anticorps (Extracellular Domain) (ABIN7543028)
Antigène
Voir toutes CD48 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- Extracellular Domain
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Fonction
- Anti-CD48 [OX-78], Rabbit IgG, kappa
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Specificité
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OX-78 binds specifically to CD48 targets and labels mouse thymocytes, B and T cells and macrophages. CD48 is a CD2 ligand and may be involved in the facilitation of interactions between activated lymphocytes. This protein is also likely to be involved in T cell activation.
Application Notes original Clone: This antibody binds CD48, and has been used in immunoprecipitation and blocking studies to identify and characterise CD48, the ligand for murine CD2 (Kato, 1992). This antibody is able to block the binding of a chimeric molecule comprised of the extracellular domain of mouse CD2 and human IgG1 Fc to T cell lines at the ligand site.
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Attributs du produit
- This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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Purification
- Protein A affinity purified
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Immunogène
- OX-78 was prepared by immunising rats against mouse CD48.
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Isotype
- IgG, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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OriginalSpeciesName: Rat
OriginalFormat: IgG2a
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD48
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Autre désignation
- CD48
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Sujet
- BCM1, BCM1 surface antigen, BLAST1, BLAST-1, HM48-1, MRC OX-45 surface antigen, MRC OX45 surface antigen, OX45 surface antigen, OX-45 surface antigen, SLAM family member 2, sgp60, sgp-60, OX78, MRC OX-78, MRC OX78
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UniProt
- P18181
Antigène
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