Recombinant CD53 anticorps

N° du produit ABIN7543047

L’anticorps Lapin Chimeric anti-CD53 a été validé pour FACS, IP, IHC (fro) et IHC (p). Il convient pour détecter CD53 dans des échantillons de Rat.

Aperçu rapide pour Recombinant CD53 anticorps (ABIN7543047)

Antigène: CD53

Type d'anticorp: Recombinant Antibody

Reactivité: Rat

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CD53 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: OX-44

Détail du produit anti-CD53 anticorps

Fonction: Anti-CD53 [OX-44], Rabbit IgG, kappa

Specificité: This antibody recognises CD53, which is expressed on peripheral T-cells, single (CD4 or CD8) positive thymocytes, B-cells, monocytes, macrophages, neutrophils, dendritic cells and microglial cells. This antibody recognises a conformational epitope that is dependent on disulphide bonding.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: This antibody was prepared by immunizing BALB/c mice with T lymphoblasts from an MLR between purified rat T helper cells and irradiated semiallogeneic rat spleen.

Isotype: IgG kappa

Information d'application

Indications d'application: This antibody binds rat CD53, and consequently labels all myeloid cells and peripheral lymphoid cells, but only 12 % of thymocytes (Paterson, 1987). Functional studies indicate that this subset of OX-44+ thymic cells includes all thymocytes that are on the pathway to immunocompetent T lymphocytes. By contrast, the OX-44- compartment represents cells that are negative for proliferation and thymopoiesic activity, and are fated to die in situ. In addition, this antibody has been used in conjunction with CD4 and CD8 antigens to define seven subsets of thymic cell. Most CD4-CD8- cells are OX-44+, whereas almost all CD4+ CD8+ cells were OX-44-

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD53

Antigène: CD53

Autre désignation: CD53

Sujet: Leukocyte surface antigen CD53, Cell surface glycoprotein CD53, Leukocyte antigen MRC OX-44

UniProt: P24485