Recombinant CD43 anticorps
Aperçu rapide pour Recombinant CD43 anticorps (ABIN7543049)
Antigène
Voir toutes CD43 (SPN) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-CD43 [OX-58], Mouse IgG2b, kappa
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Specificité
- This antibody recognises rat leukosialin, a major cell-surface sialoglycoprotein of thymocytes and T lymphocytes. It is also expressed on neutrophils, bone marrow stem cells and B-lineage cells after activation. The specificity of the leukosialin epitope is largely determined by linear protein sequence, as indicated by the reaction of this antibody with the extracellular domain of leukosialian expressed in an unglycosylated form in E. coli. However, the sensitivity of this antibody to neuraminidase treatment of leukosialin indicates that glycosylation can modify epitope conformation or flexibility.
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Attributs du produit
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Original Species of Ab: Mouse
Original Format of Ab: IgG2b
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Purification
- Protein A affinity purified
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Immunogène
- This antibody was prepared by immunizing BALB/c mice with rat thymocyte leukosialin and thymocytes.
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Isotype
- IgG2b kappa
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Indications d'application
- This antibody binds to rat leukosialin, and can be used to label thymocytes and T lymphocytes in the lymph node cell population in flow cytometry analysis. This antibody has also been used, along with other anti-CD43 MABs, in a Western blot analysis to localize leukosialin epitopes.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD43 (SPN) (Sialophorin (SPN))
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Autre désignation
- CD43
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Sujet
- Leukosialin, Leukocyte sialoglycoprotein, Sialophorin, W3/13 antigen, OX 58, MRC OX 58
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UniProt
- P13838
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Pathways
- Regulation of Leukocyte Mediated Immunity
Antigène
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