Recombinant CD43 anticorps

N° du produit ABIN7543056

L’anticorps Lapin Chimeric anti-CD43 a été validé pour WB et IP. Il convient pour détecter CD43 dans des échantillons de Rat.

Aperçu rapide pour Recombinant CD43 anticorps (ABIN7543056)

Antigène: CD43 (SPN) (Sialophorin (SPN))

Type d'anticorp: Recombinant Antibody

Reactivité: Rat

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CD43 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: OX-56

Détail du produit anti-CD43 anticorps

Fonction: Anti-CD43 [OX-56], Rabbit IgG, kappa

Specificité: OX-56 binds specifically to CD43 and binding is not affected by CD43 glycosylation. OX-56 reacts with most thymocytes and T lymphocytes in the lymph node cell population. This antibody also binds to pre-B cells and can detect CD43 at low levels on B cells. CD43 plays a role in the physicochemical properties of the T-cell surface and in lectin binding. CD43 is a major cell-surface sialoglycoprotein - also found on neutrophils, bone marrow stem cells, B-lineage cells after activation of thymocytes and T lymphocytes but is not expressed on resting B lymphocytes. The protein presents carbohydrate ligands to selectins and Is a counter-receptor for SN/Siglec-1. During T-cell activation it is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG2b

Purification: Protein A affinity purified

Immunogène: OX-56 was prepared by immunizing BALB/c mice with activated rat T lymphocytes.

Isotype: IgG kappa

Information d'application

Indications d'application: OX-56 has been used in the purification of rat leukosialin by immunoaffinty chromatography (Willis et al. 1987) as well as in WB.

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD43

Antigène: CD43 (SPN) (Sialophorin (SPN))

Autre désignation: CD43

Sujet: Leukosialin, OX56, MRC OX-56, MRC OX56, sialophorin

UniProt: P13838

Pathways: Regulation of Leukocyte Mediated Immunity