Recombinant EGFR (Nimotuzumab Biosimilar) anticorps

N° du produit ABIN7543063

Cet anticorps anti-EGFR (Nimotuzumab Biosimilar) est un anticorps Lapin Chimeric détectant EGFR (Nimotuzumab Biosimilar) dans BR, FACS et IHC. Adapté pour Humain.

Aperçu rapide pour Recombinant EGFR (Nimotuzumab Biosimilar) anticorps (ABIN7543063)

Antigène: EGFR (Nimotuzumab Biosimilar)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp EGFR (Nimotuzumab Biosimilar) est non-conjugé

Application: Blocking Reagent (BR), Flow Cytometry (FACS), Immunohistochemistry (IHC)

Clone: H-R3

Détail du produit anti-EGFR (Nimotuzumab Biosimilar) anticorps

Fonction: Anti-EGFR domain III [h-R3 (Nimotuzumab)], Rabbit IgG, kappa

Specificité: Binds to human EGFR domain III at a site distinct from antibody 7A7 (Ab00134) (Talavera et al. 2011)

Attributs du produit:

Original Species of Ab: Human

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: This antibody we generated by humanisation of the murine antibody R3, raised against EGFR purified from placenta membranes and A431 tumors.

Isotype: IgG kappa

Information d'application

Indications d'application: This antibody binds to human EGFR and inhibits EGF-dependent clonogenic growth of NRK cells and completely blocks EGF stimulated autophosphorylation of the receptor (Fernandez 1992)

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur EGFR (Nimotuzumab Biosimilar)

Antigène: EGFR (Nimotuzumab Biosimilar)

Classe de substances: Biosimilar

Sujet: ERBB-D3, ERBB1, HER1, PIG61, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, proto-oncogene c-ErbB-1, receptor tyrosine-protein kinase erbB-1, epidermal growth factor

UniProt: P00533