Recombinant ICOS anticorps

N° du produit ABIN7543074

L’anticorps Lapin Chimeric anti-ICOS a été validé pour FACS et BR. Il convient pour détecter ICOS dans des échantillons de Souris.

Aperçu rapide pour Recombinant ICOS anticorps (ABIN7543074)

Antigène: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp ICOS est non-conjugé

Application: Flow Cytometry (FACS), Blocking Reagent (BR)

Clone: 7E-17G9

Détail du produit anti-ICOS anticorps

Fonction: Anti-ICOS [7E.17G9], Rabbit IgG, kappa

Specificité: This anitbody binds to mouse ICOS (CD278).

Attributs du produit:

Original Species of Ab: Rat

Original Format of Ab: IgG2b

Purification: Protein A affinity purified

Immunogène: Rats were immunized i.m. three times with 500 mg murine ICOS cDNA in the pAXEF mammalian expression vector and boosted twice with 200 mg murine ICOS hexahistidine fusion protein.

Isotype: IgG kappa

Information d'application

Indications d'application: This antibody can be used to detect mouse ICOS by flow-cytometry. Maazi et al (2015, PMID: 25769613) showed that 7E.17G9 can inhibit ICOS interaction with its ligand ICOSL.

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur ICOS

Antigène: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Autre désignation: ICOS

Sujet: CD278, AILIM, CVID1, inducible T-cell co-stimulator, inducible T-cell costimulator, 7E.17G9.G1.G7

Pathways: Cancer Immune Checkpoints