Recombinant Desmocollin 2+3 (Extracellular Domain) anticorps

N° du produit ABIN7543132

Cet anticorps anti-Desmocollin 2+3 Chimeric Lapin (Clone 7G6) (ABIN7543132) détecte spécifiquement Desmocollin 2+3 dans IF, FACS, IHC et IP. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant Desmocollin 2+3 (Extracellular Domain) anticorps (ABIN7543132)

Antigène: Desmocollin 2+3

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Inconjugué

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: 7G6

Détail du produit

Épitope: Extracellular Domain

Fonction: Anti-desmocollin-2/3 [7G6], Rabbit IgG, kappa

Specificité:

This antibody recognizes desmocollin-2 (also known as Desmocollin-3). Desmocollins (next to desmogleins) are the main desmosomal transmembrane proteins.The expression of desmocollin-2 varies in the basal and suprabasal layers.

Application Notes original Clone: The antibody 7G6 is recommended for the detection and analysis of desmocollin-2 (desmocollin-3) via various methods, such as immunohistochemistry, Western blot and others. For instance, the antibody was used to label desmocollin-2 in primary human keratinocytes via immunohistochemistry (Franke et al., 2006). Similarly, another group detected desmocollin-2 in A431 cells (Wahl et al., 2005). The antibody 7G6 was also utilized in the assessment of expression levels of desmocollin-2 in SHEEC and KYSE510 cells via Western blot (Fang et al., 2014).

Réactivité croisée: Souris, Rat

Attributs du produit: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Purification: Protein A affinity purified

Immunogène: This antibody was raised by immunizing mice with a MBP-tagged recombinant protein corresponding to the extracellular domain of human Desmocollin-2.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

OriginalSpeciesName: Mouse

OriginalFormat: IgG1

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détail du antigène

Antigène: Desmocollin 2+3

Autre désignation: desmocollin-2/3

Sujet: Desmocollin, Desmocollin-2, Cadherin family member 2, Desmocollin-3, Desmosomal glycoprotein II, Desmosomal glycoprotein III, Cadherin family member 3, Dsc2/3, Dsc2, Dsc3, DG2, DG3

UniProt: Q02487