Recombinant Desmoglein 3 anticorps
Aperçu rapide pour Recombinant Desmoglein 3 anticorps (ABIN7543133)
Antigène
Voir toutes Desmoglein 3 (DSG3) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-desmoglein-3 [5G11], Mouse IgG1, kappa
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Specificité
- This antibody recognizes desmoglein 3. It does not cross-react with desmoglein 1 or desmoglein 2. Desmoglein-3 is a calcium binding membrane protein that is localized in desmosome cellular junctions and interacts with plaque proteins and intermediate filaments at cell-cell adhesion points.
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Attributs du produit
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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Purification
- Protein A affinity purified
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Immunogène
- This antibody was raised by immunizing Balb/c mice with a recombinant protein corresponding to human desmoglein-3.
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Isotype
- IgG1 kappa
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Indications d'application
- This antibody can be used for detection and analysis of desmoglein-3 via various methods. For instance, 5G11 was utilized todetect desmoglein-3 in human scalp hair follicles and epidermal inclusions via immunohistochemistry (Wu et al., 2003). Another group successfully used this antibody to identify desmoglein-3 via Western blot (Mao et al., 2017, pmid: 28469076). The antibody 5G11 was also used to detect DSG3 in cells via immunofluorescence (Chen et al., 2013, pmid: 23737966).
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Desmoglein 3 (DSG3)
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Autre désignation
- desmoglein-3
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Sujet
- PVA, Cadherin family member 6, desmoglein 3, 130 kDa pemphigus vulgaris antigen, DSG3
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UniProt
- P32926
Antigène
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