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Recombinant Desmoglein 3 anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement Desmoglein 3 dans WB, IHC, IF, FACS, IP et DB. Il présente une réactivité envers Humain.
N° du produit ABIN7543133

Aperçu rapide pour Recombinant Desmoglein 3 anticorps (ABIN7543133)

Antigène

Voir toutes Desmoglein 3 (DSG3) Anticorps
Desmoglein 3 (DSG3)

Type d'anticorp

Recombinant Antibody

Reactivité

  • 91
  • 21
  • 16
Humain

Hôte

  • 64
  • 47
Souris

Clonalité

  • 61
  • 48
  • 2
Monoclonal

Conjugué

  • 46
  • 9
  • 8
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Desmoglein 3 est non-conjugé

Application

  • 66
  • 35
  • 34
  • 22
  • 19
  • 13
  • 13
  • 12
  • 11
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Dot Blot (DB)

Clone

5G11
  • Fonction

    Anti-desmoglein-3 [5G11], Mouse IgG1, kappa

    Specificité

    This antibody recognizes desmoglein 3. It does not cross-react with desmoglein 1 or desmoglein 2. Desmoglein-3 is a calcium binding membrane protein that is localized in desmosome cellular junctions and interacts with plaque proteins and intermediate filaments at cell-cell adhesion points.

    Attributs du produit

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    Purification

    Protein A affinity purified

    Immunogène

    This antibody was raised by immunizing Balb/c mice with a recombinant protein corresponding to human desmoglein-3.

    Isotype

    IgG1 kappa
  • Indications d'application

    This antibody can be used for detection and analysis of desmoglein-3 via various methods. For instance, 5G11 was utilized todetect desmoglein-3 in human scalp hair follicles and epidermal inclusions via immunohistochemistry (Wu et al., 2003). Another group successfully used this antibody to identify desmoglein-3 via Western blot (Mao et al., 2017, pmid: 28469076). The antibody 5G11 was also used to detect DSG3 in cells via immunofluorescence (Chen et al., 2013, pmid: 23737966).

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    Desmoglein 3 (DSG3)

    Autre désignation

    desmoglein-3

    Sujet

    PVA, Cadherin family member 6, desmoglein 3, 130 kDa pemphigus vulgaris antigen, DSG3

    UniProt

    P32926
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