Recombinant KRT14 anticorps (AA 458-472)

N° du produit ABIN7543316

Cet anticorps Lapin Chimeric détecte spécifiquement KRT14 dans IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant KRT14 anticorps (AA 458-472) (ABIN7543316)

Antigène: KRT14 (Keratin 14 (KRT14))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp KRT14 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Clone: 2G4

Détail du produit anti-KRT14 anticorps

Épitope: AA 458-472

Fonction: Anti-Cytokeratin 14 [2G4], Rabbit IgG, kappa

Specificité: This antibody is capable of binding human cytokeratin 14. Cytokeratins are intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: The original antibody was generated by immunizing 4-6 weeks old female ICR mice with recombinant protein comprising amino acids 458-472 of cytokeratin 7 in equal volume of Freund's incomplete adjuvant.

Isotype: IgG kappa

Information d'application

Indications d'application: The binding characterization of this antibody was done using ELISA. The original IgG1 antibody binds cytokeratin 5/6 with a high affinity constant of 4.8x 10^(8) M^(-1). This antibody was also used in the immunohistochemical analysis of frozen paraffin sections of tonsil tissues and esophageal squamous cell carcinoma. The immunohistochemical staining pattern of this antibody is similar to commercially available antibody L1002 (CN113087793).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur KRT14

Antigène: KRT14 (Keratin 14 (KRT14))

Autre désignation: Cytokeratin 14

Sujet: CK14, CK-14, CK 14, K14, KRT14, keratin type I cytoskeletal 14, cytokeratin-14, keratin-14, CGMCC NO 20761, L1002

UniProt: P02533