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Recombinant Laminin anticorps

Cet anticorps anti-Laminin est un anticorps Human Monoclonal détectant Laminin dans ELISA, WB, IF et FACS. Adapté pour Humain.
N° du produit ABIN7543381

Aperçu rapide pour Recombinant Laminin anticorps (ABIN7543381)

Antigène

Voir toutes Laminin (LAMA2) Anticorps
Laminin (LAMA2) (Laminin, alpha 2 (LAMA2))

Type d'anticorp

Recombinant Antibody

Reactivité

  • 34
  • 27
  • 17
  • 16
  • 15
  • 1
  • 1
Humain

Hôte

  • 33
  • 2
Human

Clonalité

  • 32
  • 2
  • 1
Monoclonal

Conjugué

  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Laminin est non-conjugé

Application

  • 13
  • 13
  • 12
  • 6
  • 5
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
ELISA, Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone

C3_Hu10
  • Fonction

    Anti-Laminin-2 LG5 [C3_Hu10], Human IgG1, kappa

    Specificité

    This antibody recognizes human and mouse laminin-2 LG5 and LG4/5 domain. Laminin is a large extracellular heterotrimeric glycoprotein and a major constituent of the basement membrane. It is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

     Réactivité croisée

    Souris

    Attributs du produit

    Original Species of Ab: Human

    Original Format of Ab: IgG1

    Purification

    Protein A affinity purified

    Immunogène

    The original antibody was generated by immunizing Balb/c and Trianni mice with human laminin-2 LG5 domain. Humanized version was generated by grafting CDRs of parental mouse antibody C3 onto human framework regions.

    Isotype

    IgG1 kappa
  • Indications d'application

    The binding specificity of this antibody for human and mouse laminin-2 LG5 was confirmed using ELISA. This antibody is capable of detecting human and mouse LG-4/5 expressed on HEK293 in a flow cytometry. This antibody can also be used for the identification recombinant human laminin-2 (Hu 211), murine LG-5 (mLG5), human LG-5 (hLG5), and human LG-4/5 (hLG4/LG5) in a western blot. This antibody was also used for the immunofluorescent staining of unfixed human and mouse muscle tissues. This antibody was used in combination with anti-laminin-2 antibody AS30_Hu6 to generate a duobody called TBTI (US11254737).

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    Laminin (LAMA2) (Laminin, alpha 2 (LAMA2))

    Autre désignation

    Laminin-2 LG5

    Sujet

    Merosin, Laminin subunit alpha-2, LAMA2, Laminin 211, laminin G-like 5 domain, LG5, g-like 4 and 5 domain, LG-4/5, Laminin M chain, Laminin-12 subunit alpha, Laminin-2 subunit alpha, Laminin-4 subunit alpha, Merosin heavy chain, C3, humanized C3

    UniProt

    P24043, Q60675
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