Recombinant OCT4 anticorps

N° du produit ABIN7543402

Cet anticorps anti-OCT4 est un anticorps Souris Monoclonal détectant OCT4 dans WB et IHC. Adapté pour Humain.

Aperçu rapide pour Recombinant OCT4 anticorps (ABIN7543402)

Antigène: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp OCT4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 41B1

Détail du produit anti-OCT4 anticorps

Fonction: Anti-Oct3/4 [41B1], Mouse IgG2b, kappa

Specificité: The original antibody is specific for OCT3/4. OCT3/4 is a transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). It forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. It is critical for early embryogenesis and for embryonic stem cell pluripotency.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG2b

Purification: Protein A affinity purified

Immunogène: The original antibody was generated by immunizing mice with recombinant protein OCT3/4.

Isotype: IgG2b kappa

Information d'application

Indications d'application: The antibody 41B1 and the commercial antibody C-10 were used to stain collagen tumor, dysgerminoma and testicular tissue in immunohistochemistry. Results showed the antibody specificity is comparable to the commercial antibody. Further, the staining intensity of the antibody 41B1 was higher than the commercial antibody (CN113072642A).

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur OCT4

Antigène: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Autre désignation: Oct3/4

Sujet: C-10, KS20.8, POU5F1, Oct4, POU domain, class 5, transcription factor 1, POU domain, class 5, transcription factor 1, Octamer-binding protein 3, Oct-3, Octamer-binding protein 4, Oct-4, Octamer-binding transcription factor 3, OTF-3, CGMCC NO 20779

UniProt: Q01860

Pathways: Stem Cell Maintenance