Recombinant TIM3 anticorps (Extracellular Domain)
Aperçu rapide pour Recombinant TIM3 anticorps (Extracellular Domain) (ABIN7543404)
Antigène
Voir toutes TIM3 (TIM 3) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- Extracellular Domain
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Fonction
- Anti-TIM-3 [7H2], Rabbit IgG, kappa
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Specificité
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The original antibody is specific for TIM-3. TIM-3 is a type I transmembrane protein and contains an immunoglobulin and a mucin-like domain in its extracellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion.
Application Notes original Clone: The antibody specifically detected TIM-3 protein in Western blot analysis. The antibody 7H2 and the commercial antibody D5D5R were used to stain tonsils and appendix tissue. Results showed the antibody specificity is comparable to the commercial antibody (CN113234158A).
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Attributs du produit
- This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
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Purification
- Protein A affinity purified
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Immunogène
- The original antibody was generated by immunizing mice with recombinant TIM-3 protein.
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Isotype
- IgG, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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OriginalSpeciesName: Mouse
OriginalFormat: IgG1
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
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Autre désignation
- TIM-3
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Sujet
- CD366, Hepatitis A virus cellular receptor 2, Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, D5D5R, E3, CGMCCNO 20763
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UniProt
- Q8TDQ0
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Pathways
- Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
Antigène
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