Recombinant HbA1c anticorps (N-Term)

N° du produit ABIN7543441

Cet anticorps anti-HbA1c Chimeric Lapin (Clone 1G8) (ABIN7543441) détecte spécifiquement HbA1c dans ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant HbA1c anticorps (N-Term) (ABIN7543441)

Antigène: HbA1c (Glycated Hemoglobin HbA1c (HbA1c))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp HbA1c est non-conjugé

Application: ELISA

Clone: 1G8

Détail du produit anti-HbA1c anticorps

Épitope: N-Term

Fonction: Anti-HbA1c [1G8], Rabbit IgG, kappa

Specificité:

This antibody binds human hemoglobin glycated at the N-terminal valine of the hemoglobin β chain and does not cross react with non-glycated hemoglobin. Glycated hemoglobin is formed by the conjugation of a hexose sugar to the beta-chain of hemoglobin. Glycosylated hemoglobin A1c (HbA1c) levels are used as an indicator of average plasma glucose concentration in diabetic patients. Levels of more than 48 mmol/mol (6.5 % ) are used as a criterion for the diagnosis of diabetes. Higher levels of HbA1c are also associated with cardiovascular disease.

Application Notes original Clone: This antibody is recommended for detection of HbA1c levels in plasma and blood samples. The binding reactivity of this antibody towards HbA1c and non-glycated hemoglobin was done using indirect ELISA. The binding reactivity of this antibody to HbA1c was compared to commercially available anti-HbA1c antibody BM300-F7C2 and it was reported that this antibody showed better specificity for HbA1c (CN110724671).

Attributs du produit: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Purification: Protein A affinity purified

Immunogène: The original antibody was generated by immunizing BALB/c mice with synthetic N-terminal glycopeptide (VHLTPEC) and KLH conjugate.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

OriginalSpeciesName: Mouse

OriginalFormat: IgG2a

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur HbA1c

Antigène: HbA1c (Glycated Hemoglobin HbA1c (HbA1c))

Autre désignation: HbA1c

Sujet: GHb, A1C, HBB, hemoglobin A1c, glycosylated hemoglobin HbA1c, glycosylated hemoglobin, glycohemoglobin, glycated hemoglobin, haemoglobin, haemoglobin A1c, Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain

UniProt: P68871