Recombinant NCR1 anticorps

N° du produit ABIN7543464

L’anticorps anti-NCR1 Chimeric Lapin est utilisé pour la détection de NCR1 dans des échantillons de Souris. Il a été validé pour FACS et Act.

Aperçu rapide pour Recombinant NCR1 anticorps (ABIN7543464)

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp NCR1 est non-conjugé

Application: Flow Cytometry (FACS), Activation (Act)

Clone: 29A1-4

Détail du produit anti-NCR1 anticorps

Fonction: Anti-Nkp46 [29A1.4], Rabbit IgG, kappa

Specificité:

This antibody is specific for mouse NKp46-Fc.

Application Notes original Clone: The original format of this antibody was used in an FC analysis to detect NKp46 expression on NK cells and to activate NK in an NK cell stimulation assay (Walzer et al., 2007, PMID: 17360655). This antibody was used as a component of bispecific NKCEs (Natural Killer Cell Engagers) to redirect the cytotoxic activity of NK cells towards human CD20-expressing tumor cells in a transplantable xenogeneic in vivo solid tumor model (Gauthier et al., 2019, PMID: 31155232).

Attributs du produit: This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Purification: Protein A affinity purified

Immunogène: The original antibody was generated by immunizing rats with mouse NKp46-Fc recombinant protein.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

OriginalSpeciesName: Rat

OriginalFormat: IgG2a

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur NCR1

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Autre désignation: Nkp46

Sujet: CD335, NK-p46, NKp46, mNKp46, mAR-1, Activating receptor 1, Lymphocyte antigen 94, Natural killer cell p46-related protein, Natural cytotoxicity triggering receptor 1

UniProt: Q8C567

Pathways: Regulation of Leukocyte Mediated Immunity