Recombinant NCR1 anticorps

N° du produit ABIN7543465

Cet anticorps anti-NCR1 est un anticorps Rat Monoclonal détectant NCR1 dans FACS et Act. Adapté pour Souris.

Aperçu rapide pour Recombinant NCR1 anticorps (ABIN7543465)

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp NCR1 est non-conjugé

Application: Flow Cytometry (FACS), Activation (Act)

Clone: 29A1-4

Détail du produit anti-NCR1 anticorps

Fonction: Anti-Nkp46 [29A1.4], Rat IgG2a, kappa

Specificité: This antibody is specific for mouse NKp46-Fc.

Attributs du produit:

Original Species of Ab: Rat

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogène: The original antibody was generated by immunizing rats with mouse NKp46-Fc recombinant protein.

Isotype: IgG2a kappa

Information d'application

Indications d'application: The original format of this antibody was used in an FC analysis to detect NKp46 expression on NK cells and to activate NK in an NK cell stimulation assay (Walzer et al., 2007, PMID: 17360655). This antibody was used as a component of bispecific NKCEs (Natural Killer Cell Engagers) to redirect the cytotoxic activity of NK cells towards human CD20-expressing tumor cells in a transplantable xenogeneic in vivo solid tumor model (Gauthier et al., 2019, PMID: 31155232).

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur NCR1

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Autre désignation: Nkp46

Sujet: CD335, NK-p46, NKp46, mNKp46, mAR-1, Activating receptor 1, Lymphocyte antigen 94, Natural killer cell p46-related protein, Natural cytotoxicity triggering receptor 1

UniProt: Q8C567

Pathways: Regulation of Leukocyte Mediated Immunity