Metronidazole anticorps (Biotin)

N° du produit ABIN723173

Détail du produit

Antigène: Metronidazole

Reactivité: Chemical

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Purified by Protein G.

Immunogène: KLH conjugated with Metronidazole

Clone: 1C2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4°C

Date de péremption: 12 months

Détail du antigène

Antigène: Metronidazole

Classe de substances: Chemical

Sujet:

Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa. Metronidazole is an antibiotic, amebicide, and antiprotozoal.Metronidazole, taken up by diffusion, is selectively absorbed by anaerobic bacteria and sensitive protozoa. Once taken up by anaerobes, it is non-enzymatically reduced by reacting with reduced ferredoxin, which is generated by pyruvate oxido-reductase. Many of the reduced nitroso intermediates will form sulfinamides and thioether linkages with cysteine-bearing enzymes, thereby deactivating these critical enzymes. As many as 150 separate enzymes are affected.In addition or alternatively, the metronidazole metabolites are taken up into bacterial DNA, and form unstable molecules. This function only occurs when metronidazole is partially reduced, and because this reduction usually happens only in anaerobic cells, it has relatively little effect upon human cells or aerobic bacteria.

Synonyms: 2-Methyl-5-nitroimidazole-1-ethanol