ACTH 7-23 anticorps

N° du produit ABIN723485

Détail du produit

Antigène: ACTH 7-23

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Pig,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ACTH

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Référence

Jussila, Huotari-Orava, Ylianttila, Partonen, Snellman: "Narrow-band ultraviolet B radiation induces the expression of β-endorphin in human skin in vivo." dans: Journal of photochemistry and photobiology. B, Biology, Vol. 155, pp. 104-8, (2016) (PubMed).

Zhou, Wei, Kuang, Luo, Ma, Zeng, Wang, Liu, Gong, Wang, Lei, Wang, Zeng, Wang, He, Yuan, Dai, He, Xing: "A novel P53/POMC/Gαs/SASH1 autoregulatory feedback loop activates mutated SASH1 to cause pathologic hyperpigmentation." dans: Journal of cellular and molecular medicine, Vol. 21, Issue 4, pp. 802-815, (2016) (PubMed).

Détail du antigène

Antigène: ACTH 7-23

Sujet:

Synonyms: Adrenocorticotropic hormone, Adrenocorticotropin, Adrenocorticotropin Hormone, Alpha Melanocyte Stimulating Hormone, Beta Endorphin, Beta Lipotropin, Beta Melanocyte Stimulating Hormone, CLIP, Corticotropin, Corticotropin Like Intermediary Peptide, Corticotropin lipotropin precursor, Lipotropin Beta, Lipotropin Gamma, LPH, Melanotropin Alpha, Met Enkephalin, MSH, NPP, POC, POMC, Pro opiomelanocortin, Proopiomelanocortin.

Background: ACTH occurs in cells of the anterior pituitary and in neurons in brain. It regulates the corticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin are endogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes.

ID gène: 5443

UniProt: P01189