PP2A alpha/beta anticorps (AA 205-309)

N° du produit ABIN723875

L’anticorps Lapin Polyclonal anti-PP2A alpha/beta a été validé pour WB, IF (cc), IF (p), ELISA, FACS, IHC (p) et IHC (fro). Il convient pour détecter PP2A alpha/beta dans des échantillons de Humain et Souris. Il y a 2+ publications disponibles.

Aperçu rapide pour PP2A alpha/beta anticorps (AA 205-309) (ABIN723875)

Antigène: PP2A alpha/beta (PP2A A/B)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PP2A alpha/beta est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-PP2A alpha/beta anticorps

Épitope: AA 205-309

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PP-2A

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-PP2A alpha/beta (ABIN723875)

Lin, Bo, Tan, Sun, Song, Zhao, Ma, Li, Zheng, Xu: "Feasibility of ?-Sheet Breaker Peptide-H102 Treatment for Alzheimer's Disease Based on ?-Amyloid Hypothesis." dans: PLoS ONE, Vol. 9, Issue 11, pp. e112052, (2014) (PubMed).

Zhao, Di, Liu, Liu, Lai, Lü: "Involvement of GSK3 and PP2A in ginsenoside Rb1's attenuation of aluminum-induced tau hyperphosphorylation." dans: Behavioural brain research, Vol. 241, pp. 228-34, (2013) (PubMed).

Détails sur PP2A alpha/beta

Antigène: PP2A alpha/beta (PP2A A/B)

Autre désignation: PP2A alpha / beta

Sujet:

Synonyms: RP-C, PP2Ac, PP2CA, PP2Calpha, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, PPP2CA

Background: PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV4 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.

ID gène: 5515

UniProt: P67775