PP2A alpha/beta anticorps (AA 205-309) (Cy7)

N° du produit ABIN723881

L’anticorps anti-PP2A alpha/beta Polyclonal Lapin est utilisé pour la détection de PP2A alpha/beta dans des échantillons de Humain. Il a été validé pour WB, IF (cc), IF (p) et FACS.

Aperçu rapide pour PP2A alpha/beta anticorps (AA 205-309) (Cy7) (ABIN723881)

Antigène: PP2A alpha/beta (PP2A A/B)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PP2A alpha/beta est conjugé à/à la Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Détail du produit anti-PP2A alpha/beta anticorps (Cy7)

Épitope: AA 205-309

Fonction: PP2A alpha + beta Polyclonal Antibody, Cy7 Conjugated

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PP-2A

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PP2A alpha/beta

Antigène: PP2A alpha/beta (PP2A A/B)

Autre désignation: PP2A alpha / beta

Sujet:

Synonyms: RP-C, PP2Ac, PP2CA, PP2Calpha, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, PPP2CA

Background: PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV4 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.

ID gène: 5515

UniProt: P67775