FOLR1 anticorps (HRP)

N° du produit ABIN7565763

Cet anticorps anti-FOLR1 est un anticorps Chèvre Polyclonal détectant FOLR1 dans WB, ELISA et IP. Adapté pour Boeuf (Vache).

Aperçu rapide pour FOLR1 anticorps (HRP) (ABIN7565763)

Antigène: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Reactivité: Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp FOLR1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-FOLR1 anticorps (HRP)

Fonction: Folate Binding Protein Antibody Peroxidase Conjugated

Réactivité croisée (Details): Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Peroxidase, anti-Goat Serum as well as purified and partially purified Folate Binding Protein [Bovine Milk].

Attributs du produit: Synonyms: goat anti-Folate Binding Protein Antibody HRP Conjugation, Peroxidase Conjugated goat anti-Folate Binding Protein Antibody, Folate receptor alpha, FR-alpha, Folate receptor 1, Milk folate-binding protein, Folate-binding protein 1, FBP

Purification: Anti-Folate-binding protein is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.

Stérilité: Sterile filtered

Immunogène:

Immunogen: Folate Binding Protein [Bovine Milk]

Immunogen Type: Native Protein

Information d'application

Indications d'application: Application Note: Anti-Folate Binding Protein has been tested in western blot and is suitable to be assayed against 1.0 μg of Folate Binding Protein [Bovine Milk] in a standard capture ELISA using ABTS (2,2'-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid]) code # ABTS-100 as a substrate for 30 minutes at room temperature.  A working dilution of 1:2,000 to 1:10,000 of the reconstitution concentration is suggested for this product. Western Blot Dilution: 1:500 - 1:1,000 Immunoprecipitation Dilution: 1:100 ELISA Dilution: 1:1,000 - 1:2,500 Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 10 mg/mL Polyethylene Glycol (PEG-8000)

Preservative: 0.01 % (w/v) Gentamicin Sulfate. Do NOT add Sodium Azide!

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

Date de péremption: 12 months

Détails sur FOLR1

Antigène: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Autre désignation: FOLR1

Sujet: Background: Folate-binding protein (FBP) are proteins that bind folate, typically the folate receptors and reduced folate carrier. In cancer research it can be a marker for ovarian cancer. It can be measured to help in tumor classification to aid treatment. FBP is over-expressed (20-80 fold) in more than 90 % of ovarian and endometrial cancers, as well as 20-50 % of breast, lung, colorectal, and renal cell carcinomas. FBP has very limited tissue distribution and expression in non-malignant tissue, making it a good immunotherapy target.

ID gène: 539750

NCBI Accession: NP_001193456

UniProt: P02702

Pathways: Dicarboxylic Acid Transport