CLIC1 anticorps

N° du produit ABIN7565989

Cet anticorps Lapin Polyclonal détecte spécifiquement CLIC1 dans WB, ELISA et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour CLIC1 anticorps (ABIN7565989)

Antigène: CLIC1 (Chloride Intracellular Channel 1 (CLIC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLIC1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-CLIC1 anticorps

Fonction: CLIC1 Antibody

Réactivité croisée (Details): This antibody is specific for human CLIC1.

Attributs du produit: Synonyms: Rabbit Anti-CLIC1 Antibody, Chloride Intracellular Channel 1, Regulatory Nuclear Chloride Ion Channel Protein, Chloride Intracellular Channel Protein 1, Nuclear Chloride Ion Channel 27, Chloride Channel ABP, NCC27, HRNCC, G6, Nuclear Chloride Ion Channel Protein, RNCC Protein, P64CLCP

Purification: This product was Protein A purified from monospecific antiserum by chromatography.

Stérilité: Sterile filtered

Immunogène:

Immunogen: This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with human CLIC1 recombinant protein.

Immunogen Type: Recombinant Protein

Information d'application

Indications d'application: Application Note: Anti-CLIC1 has been tested in ELISA, Western Blot, and Immunoprecipitation. Expect a band at ~27kda in western blot using appropriate tissues and lysates. Positive controls used in western blot include CLIC1 overexpressing HEK293, WM-115, and HL-60 whole cell lysates. Western Blot Dilution: 1 μg/mL Immunoprecipitation Dilution: User Optimized ELISA Dilution: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.06 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur CLIC1

Antigène: CLIC1 (Chloride Intracellular Channel 1 (CLIC1))

Autre désignation: CLIC1

Sujet: Background: CLIC1 (Chloride Intracellular Channel 1) can insert into membranes and form chloride ion channels. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH , and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family, the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. This channel activity depends on the pH . Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle. Anti-CLIC1 is useful for researchers interested in Blackwater Fever and Penicilliosis diseases, along with Cancer, Neuroscience, and activation of cAMP-Dependent PKA.

ID gène: 1192

NCBI Accession: NP_001274522

UniProt: O00299