Recombinant CRP anticorps

N° du produit ABIN7566407

L’anticorps Human Monoclonal anti-CRP a été validé pour WB et ELISA. Il convient pour détecter CRP dans des échantillons de Humain.

Aperçu rapide pour Recombinant CRP anticorps (ABIN7566407)

Antigène: CRP (C-Reactive Protein (CRP))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Human

Clonalité: Monoclonal

Conjugué: Cet anticorp CRP est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: SH1177-F3

Détail du produit anti-CRP anticorps

Fonction: anti-CRP (human), mAb (rec.) (SH1177-F3)

Attributs du produit:

Recombinant Antibody. Recognizes human C-reactive protein (CRP). Applications: ELISA, WB. Clone: SH1177-F3. Isotype: Human IgG1. Formulation: Liquid. In PBS. C-reactive protein (CRP) is a major cyclic, pentameric acute phase protein compound consisting of five identical, noncovalently bound, nonglycosylated subunits. CRP is produced by the liver, and its plasma levels rise dramatically during inflammatory processes occurring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.), plays an important role in innate immunity and mediates activities associated with pre-immune nonspecific host resistance. Specifically, there is a 100-1000 fold increase of CRP in response to injury, infection or inflammation. CRP is opsonic, an initiator of the classical complement cascade, and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. CRP is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host, and initiates pathogen elimination by interacting with humoral and cellular effector systems in the blood. Patients with elevated basal levels of CRP have been shown to be an increased risk for hypertension and cardiovascular disease.

C-reactive protein (CRP) is a major cyclic, pentameric acute phase protein compound consisting of five identical, noncovalently bound, nonglycosylated subunits. CRP is produced by the liver, and its plasma levels rise dramatically during inflammatory processes occurring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.), plays an important role in innate immunity and mediates activities associated with pre-immune nonspecific host resistance. Specifically, there is a 100-1000 fold increase of CRP in response to injury, infection or inflammation. CRP is opsonic, an initiator of the classical complement cascade, and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. CRP is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host, and initiates pathogen elimination by interacting with humoral and cellular effector systems in the blood. Patients with elevated basal levels of CRP have been shown to be an increased risk for hypertension and cardiovascular disease.

Purification: Purified

Pureté: >95 % (SDS-PAGE)

Immunogène: Recombinant human C-reactive protein (CRP).

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS.

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.Please handle under sterile conditions to avoid contamination.

Stock: 4 °C,-20 °C

Stockage commentaire:

Stable for at least 1 year after receipt when stored at -20°C.

Stable for at least 1 week when stored at +4°C.

Détails sur CRP

Antigène: CRP (C-Reactive Protein (CRP))

Autre désignation: CRP

UniProt: P02741

Pathways: Carbohydrate Homeostasis