LAG3 anticorps

N° du produit ABIN7566431

L’anticorps Souris Monoclonal anti-LAG3 a été validé pour WB, ELISA, IHC, IP, ICC et Func. Il convient pour détecter LAG3 dans des échantillons de Humain et Singe.

Aperçu rapide pour LAG3 anticorps (ABIN7566431)

Antigène: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LAG3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func)

Clone: 11E3

Détail du produit anti-LAG3 anticorps

Fonction: anti-LAG-3, mAb (blocking) (11E3) (preservative free)

Attributs du produit:

Monoclonal Antibody. Recognizes human and monkey LAG-3. Isotype: Mouse IgG1. Clone: 1.10E+04. Applications: ELISA, FUNC (Blocking), ICC, IHC, IP, WB. Liquid. In PBS. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

Purification: Puified

Pureté: >95 % (SDS-PAGE)

niveau d'endotoxine: <0.001EU/μg purified protein or <1EU/mg purified protein (LAL test, Lonza).

Immunogène: Recombinant human LAG-3.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: In PBS.

Agent conservateur: Without preservative

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

Stable for at least 1 year after receipt when stored at -20°C.

Détails sur LAG3

Antigène: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Autre désignation: LAG-3

UniProt: P18627

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints