2B4 anticorps (PE,Cy5)
Aperçu rapide pour 2B4 anticorps (PE,Cy5) (ABIN7566585)
Antigène
Voir toutes 2B4 (CD244) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- PE/Cyanine5 Anti-Human CD244 Antibody[C1.7]
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Isotype
- IgG1, kappa
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Indications d'application
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Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
FCM: 5 µL/test -
Commentaires
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Matching Isotype Control:
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
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Stock
- 4 °C
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Stockage commentaire
- This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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Date de péremption
- 12 months
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- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
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Autre désignation
- CD244
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Sujet
- 2B4,SLAMF4,CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including most CD8+ T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression.
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ID gène
- 51744
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UniProt
- Q9BZW8
Antigène
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