PD-1 anticorps (Elab Fluor®700)

N° du produit ABIN7566875

L’anticorps Rat Monoclonal anti-PD-1 a été validé pour FACS. Il convient pour détecter PD-1 dans des échantillons de Souris.

Aperçu rapide pour PD-1 anticorps (Elab Fluor®700) (ABIN7566875)

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp PD-1 est conjugé à/à la Elab Fluor®700

Application: Flow Cytometry (FACS)

Clone: 29F-1A12

Détail du produit anti-PD-1 anticorps (Elab Fluor®700)

Fonction: Elab Fluor®700 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10 cells in 100 μL volume].

Commentaires:

Matching Isotype Control: E-AB-F09833M1

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Stock: 4 °C

Stockage commentaire: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Date de péremption: 12 months

Détails sur PD-1

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Autre désignation: CD279/PD-1

Sujet: Programmed Death-1,PD-1,CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

ID gène: 18566

UniProt: Q02242

Pathways: Cancer Immune Checkpoints