GCH1 anticorps (AA 34-110) (HRP)

N° du produit ABIN725519

L’anticorps Lapin Polyclonal anti-GCH1 a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter GCH1 dans des échantillons de Souris.

Aperçu rapide pour GCH1 anticorps (AA 34-110) (HRP) (ABIN725519)

Antigène: GCH1 (GTP Cyclohydrolase 1 (GCH1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCH1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-GCH1 anticorps (HRP)

Épitope: AA 34-110

Réactivité croisée: Souris

Homologie: Human,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GTP-CH-1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GCH1

Antigène: GCH1 (GTP Cyclohydrolase 1 (GCH1))

Autre désignation: GTP cyclohydrolase 1

Sujet:

Synonyms: GTP-CH-1, DYT 5, DYT5, GCH 1, GCH, GCH1, GTP CH 1, GTP CH I, GTP cyclohydrolase 1 dopa responsive dystonia, GTP cyclohydrolase 1, GTP cyclohydrolase I, GTPCH 1, GTPCH1, Guanosine 5' triphosphate cyclohydrolase I.

Background: GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.

ID gène: 2643