Estrogen Receptor alpha + beta (AA 201-300) anticorps

N° du produit ABIN725855

L’anticorps Lapin Polyclonal anti- a été validé pour WB, IF (cc), IF (p), ELISA, IHC (fro) et IHC (p). Il convient pour détecter dans des échantillons de Humain et Rat. Il y a 1 publication disponible.

Aperçu rapide pour Estrogen Receptor alpha + beta (AA 201-300) anticorps (ABIN725855)

Antigène: Estrogen Receptor alpha + beta

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Épitope: AA 201-300

Réactivité croisée: Humain, Rat

Homologie: Mouse,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Estradiol Receptor alpha + beta

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Référence

Li, Yang, Yang, Guo, Zhang, Yang, Li: "Antiosteoporotic activity of echinacoside in ovariectomized rats." dans: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 20, Issue 6, pp. 549-57, (2013) (PubMed).

Détail du antigène

Antigène: Estrogen Receptor alpha + beta

Sujet:

Synonyms: Estrogen Receptor alpha/beta, Atherosclerosis, susceptibility to, included, DKFZp686N23123, ER Alpha, ER, ER Beta, ER-alpha, ER-beta, ER[a], ER[b], Era, ERalpha, Erb, Erb2, ERbeta, ESR, ESR BETA, ESR1, ESR1_HUMAN, ESR2, ESRA, ESRB, Estr, Estra, Estradiol Receptor alpha, Estradiol receptor, Estradiol Receptor beta, ESTRB, Estrogen receptor 1 alpha, Estrogen Receptor 1, Estrogen receptor 2 ER beta, Estrogen Receptor 2, Estrogen receptor 2 ER beta, Estrogen receptor alpha, Estrogen receptor, Estrogen receptor beta 4, Estrogen resistance, included, HDL cholesterol, augmented response of, to hormone replacement, included, Myocardial infarction, susceptibility to, included, NR3A1, NR3A2, Nuclear receptor subfamily 3 group A member 1, Nuclear receptor subfamily 3 group A member 2, OTTHUMP00000017718, OTTHUMP00000017719, RNESTROR.

Background: The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER beta has recently been described. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen) therapy.

ID gène: 2099, 2100