Recombinant CRP anticorps

N° du produit ABIN7581768

L’anticorps Souris Monoclonal anti-CRP a été validé pour ELISA. Il convient pour détecter CRP dans des échantillons de Humain.

Aperçu rapide pour Recombinant CRP anticorps (ABIN7581768)

Antigène: CRP (C-Reactive Protein (CRP))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CRP est non-conjugé

Application: ELISA

Classe de qualité: Animal-Free

Clone: AB469-1-A05

Détail du produit anti-CRP anticorps

Expression System: Phage display

Fonction: Mouse Anti- human C-reactive protein (CRP)

Specificité: This is an antibody developed by antibody phage display technology using a human naive antibody gene library and human C-reactive protein (CRP) antigen. For this antibody both the heavy and light chains are cloned and expressed, generating full-length antibodies.

Attributs du produit: This antibody can be detected with anti-mouse Fc secondary antibodies.

Purification: Protein A purification

Immunogène: No immunization, animal-free antibody development. Antigen: human C-reactive protein

Isotype: IgG2a

Information d'application

Indications d'application: ELISA: 1-12 μg/mL as coating antibody 0.5-5 μg/mL as detection antibody Optimal working dilution should be determined by the investigator

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4,

Stock: -20 °C

Détails sur CRP

Antigène: CRP (C-Reactive Protein (CRP))

Autre désignation: C-reactive Protein

Sujet: C-reactive protein (CRP) is an important acute-phase protein produced by the liver in response to inflammation, primarily triggered by the cytokine interleukin-6 (IL-6). Structurally, CRP is a pentamer composed of five identical subunits, which enables it to bind to phosphocholine on the surfaces of dead or dying cells and certain bacteria. This binding facilitates the activation of the complement system and enhances phagocytosis, playing a crucial role in the innate immune response. Clinically, elevated CRP levels in the blood serve as a non-specific marker of inflammation, making it useful for diagnosing and monitoring conditions such as infections, autoimmune disorders, and inflammatory diseases like rheumatoid arthritis and inflammatory bowel disease (IBD). High-sensitivity CRP (hs-CRP) tests are also utilized to assess the risk of cardiovascular diseases, including heart attacks and strokes, by detecting low levels of chronic inflammation. In summary, C-reactive protein is a key indicator of inflammation and immune system activity, widely used in medical diagnostics to evaluate and monitor various inflammatory and infectious conditions.

Poids moléculaire: 115 kDa

ID gène: 1401

NCBI Accession: NG_013007

UniProt: P02741

Pathways: Carbohydrate Homeostasis