GOT1 anticorps

N° du produit ABIN7595314

Cet anticorps anti-GOT1 est un anticorps Cobaye Polyclonal détectant GOT1 dans WB, IHC et IHC (p). Adapté pour Rat.

Aperçu rapide pour GOT1 anticorps (ABIN7595314)

Antigène: GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))

Reactivité: Rat

Hôte: Cobaye

Clonalité: Polyclonal

Conjugué: Cet anticorp GOT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GOT1 anticorps

Fonction: Guinea pig antibody to Aspartate Aminotransferase (AATC)

Specificité: Specific for AATC

Réactivité croisée: Humain, Souris, Rat

Purification: Whole serum

Immunogène: A synthetic peptide from rat AATC conjugated to blue carrier protein was used as the antigen.

Information d'application

Indications d'application: IHC WB. A dilution of 1: 500 is recommended for IHC-P,WB. The optimal dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur GOT1

Antigène: GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))

Autre désignation: Aspartate Aminotransferase

Sujet: Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate regulates levels of mercaptopyruvate an important source of hydrogen sulfide. Mercaptopyruvate is converted into H2S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.

Pathways: Hepatitis C, Monocarboxylic Acid Catabolic Process, Methionine Biosynthetic Process