DNMT3L anticorps (AA 1-387) (FL490)

N° du produit ABIN7595411

Cet anticorps Souris Monoclonal détecte spécifiquement DNMT3L dans ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour DNMT3L anticorps (AA 1-387) (FL490) (ABIN7595411)

Antigène: DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DNMT3L est conjugé à/à la FL490

Application: Immunocytochemistry (ICC)

Clone: N117-9

Détail du produit anti-DNMT3L anticorps (FL490)

Épitope: AA 1-387

Fonction: Anti-DNMT3L Antibody FL490 Conjugate

Specificité: No off-targets reported for DNMT3A or DNMT3B

Réactivité croisée: Humain

Attributs du produit:

Description: Our Anti-DNMT3L mouse monoclonal primary antibody is produced in-house from hybridoma clone N117/9. It detects human DNMT3L, and is purified by Protein A chromatography. It is great for use in ICC.

Manufacturer Comment: We produce our DNMT3L mouse monoclonal primary antibody from hybridoma clone N117/9. It is great in ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Pureté: > 90 % specific antibody

Immunogène: Fusion protein amino acids 1-387 (full-length) of human DNMT3L (accession number BAA95556) produced recombinantly in E. Coli

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Date de péremption: 12 months

Détails sur DNMT3L

Antigène: DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

Autre désignation: DNMT3L

Sujet:

Synonyms: DNA (cytosine-5)-methyltransferase 3-like

Target Description: DNA (cytosine-5)-methyltransferase 3-like or DNMT3L is encoded by the gene DNMT3L. DNMT3l is a nuclear, catalytically inactive, regulatory factor of DNA methyltransferases. DNMT3L mediates transcriptional repression through interaction with histone deacetylase 1. It is thought to be required for the establishment of maternal genomic imprints. DNMT3L is expressed in several tissues including testis, ovary, and thymus. Diseases associated with DNMT3L include Testicular Spermatocytic Seminoma and Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome.

Gene Name Alternatives: DNMT3L

Poids moléculaire: 45 kDa