HCN4 anticorps (AA 1019-1108) (FL490)

N° du produit ABIN7595482

Cet anticorps anti-HCN4 est un anticorps Souris Monoclonal détectant HCN4 dans IHC et ICC. Adapté pour Rat.

Aperçu rapide pour HCN4 anticorps (AA 1019-1108) (FL490) (ABIN7595482)

Antigène: HCN4 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 4 (HCN4))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HCN4 est conjugé à/à la FL490

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N114-10

Détail du produit anti-HCN4 anticorps (FL490)

Épitope: AA 1019-1108

Fonction: Anti-HCN4 Antibody FL490 Conjugate

Specificité: No off-targets reported for other HCN's

Réactivité croisée: Gerbille, Humain, Souris, Porc, Rat

Attributs du produit:

Description: Our Anti-HCN4 mouse monoclonal primary antibody is produced in-house from hybridoma clone N114/10. It detects human, mouse, and rat HCN4, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our HCN4 mouse monoclonal primary antibody from hybridoma clone N114/10. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Pureté: > 90 % specific antibody

Immunogène: Fusion protein amino acids 1019-1108 (cytoplasmic C-terminus) of rat HCN4 (accession number Q9JKA7) produced recombinantly in E. Coli

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Date de péremption: 12 months

Détails sur HCN4

Antigène: HCN4 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 4 (HCN4))

Autre désignation: HCN4

Sujet:

Synonyms: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

Target Description: HCN4 is a member of the hyperpolarization-activated cyclic nucleotide gated channel family, also known as pacemaker channels. This family has a role in rhythmic activity of the heart and firing neurons. HCN channels are made up of four subunits, HCN1-4 and can be formed in multiple combinations. HCN4 is found in the cell membrane as a multi pass membrane protein in the sino-atrial node of the heart. This protein is highly expressed in neurons in the thalamus and other brain regions and testis. Mutations in HCN4 have been found in several types of sinus bradycardia.

Gene Name Alternatives: HCN4

Poids moléculaire: 130 kDa