Neuroligin 1 anticorps (AA 718-843) (FL490)

N° du produit ABIN7595501

Cet anticorps Souris Monoclonal détecte spécifiquement Neuroligin 1 dans IHC et ICC. Il présente une réactivité envers Rat.

Aperçu rapide pour Neuroligin 1 anticorps (AA 718-843) (FL490) (ABIN7595501)

Antigène: Neuroligin 1 (NLGN1)

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Neuroligin 1 est conjugé à/à la FL490

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N97A-31

Détail du produit anti-Neuroligin 1 anticorps (FL490)

Épitope: AA 718-843

Fonction: Anti-Neuroligin-1 Antibody FL490 Conjugate

Specificité: No off-targets reported for Neuroligin-2, -3, -4 or -4*

Réactivité croisée: Poulet, Humain, Souris, Rat

Attributs du produit:

Description: Our Anti-Neuroligin-1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N97A/31. It is KO validated, detects mouse and rat Neuroligin-1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our Neuroligin-1 mouse monoclonal primary antibody from hybridoma clone N97A/31. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Pureté: > 90 % specific antibody

Immunogène: Fusion protein amino acids 718-843 (intracellular C-terminus) of rat Neuroligin-1 (accession number NP_446320) produced recombinantly in E. Coli

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Date de péremption: 12 months

Détails sur Neuroligin 1

Antigène: Neuroligin 1 (NLGN1)

Autre désignation: Neuroligin-1

Sujet:

Synonyms: Neuroligin-1 (Neuroligin I)

Target Description: Neuroligin 1 is a member of a large family of alternatively sliced proteins located at the post synaptic surface in the central nervous system, and stains as a post synaptic marker. Neuroligin 1 is involved in cell-cell-interactions by binding to neurexin family members and other postsynaptic proteins to localize receptors and channels in the postsynaptic density. Suggested roles for Neuroligin 1 include synapse function and synaptic signal transmission and maintaining synapse integrity. Mutations in Neuroligans have been implicated in autism and other cognitive disorders.

Gene Name Alternatives: Nlgn1

Poids moléculaire: 120 kDa

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis