CADM1 anticorps (AA 257-388) (FL550)

N° du produit ABIN7595572

Cet anticorps anti-CADM1 est un anticorps Souris Monoclonal détectant CADM1 dans ICC. Adapté pour Souris.

Aperçu rapide pour CADM1 anticorps (AA 257-388) (FL550) (ABIN7595572)

Antigène: CADM1 (Cell Adhesion Molecule 1 (CADM1))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CADM1 est conjugé à/à la FL550

Application: Immunocytochemistry (ICC)

Clone: L45-30

Détail du produit anti-CADM1 anticorps (FL550)

Épitope: AA 257-388

Fonction: Anti-SynCAM1 Antibody FL550 Conjugate

Specificité: No cross-reactivity with SynCAM2 or SynCAM3

Réactivité croisée: Humain, Souris, Rat

Attributs du produit:

Description: Our Anti-SynCAM1 mouse monoclonal primary antibody is produced in-house from hybridoma clone L45/30. It detects human, mouse, and rat SynCAM1, and is purified by Protein A chromatography. It is great for use in ICC.

Manufacturer Comment: We produce our SynCAM1 mouse monoclonal primary antibody from hybridoma clone L45/30. It is great in ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Pureté: > 90 % specific antibody

Immunogène: Fusion protein amino acids 257-388 of mouse SynCAM1 (accession number Q8R5M8), recognizes 1.4b isoform only (epitope narrowed to GLTQLPNSAEELDSEDLS) produced recombinantly in E. Coli

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Date de péremption: 12 months

Détails sur CADM1

Antigène: CADM1 (Cell Adhesion Molecule 1 (CADM1))

Autre désignation: SynCAM1

Sujet:

Synonyms: Cell adhesion molecule 1 (Immunoglobulin superfamily member 4) (IgSF4) (Nectin-like protein 2) (NECL-2) (Spermatogenic immunoglobulin superfamily) (SgIgSF) (Synaptic cell adhesion molecule) (SynCAM) (Tumor suppressor in lung cancer 1) (TSLC-1)

Target Description: SynCAM1 cell adhesion molecule, Immunoglobulin superfamily member 4 (IgSF4), or Nectin-like protein 2 (NECL-2) is encoded by the gene CADM1 and is a member of the Immunoglobulin-like Cell Adhesion Molecules family. SynCam1 is a cell adhesion molecule involved in many cell processes including the mediation of cell-cell adhesion and assembly, neuronal migration axon growth and differentiation. SynCAM1 is expressed in many tissue types including, brain, lung, kidney, heart, spleen and liver. Diseases associated with this gene include Retroperitoneal Fibrosis and Neuromyelitis Optica Spectrum Disorder.

Gene Name Alternatives: Cadm1 Igsf4 Necl2 Ra175 Syncam SynCam1 Tslc1

Poids moléculaire: 50 kDa

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Activated T Cell Proliferation