GSG2 anticorps (AA 1-798) (FL594)

N° du produit ABIN7595680

Cet anticorps anti-GSG2 est un anticorps Souris Monoclonal détectant GSG2 dans ICC. Adapté pour Humain.

Aperçu rapide pour GSG2 anticorps (AA 1-798) (FL594) (ABIN7595680)

Antigène: GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GSG2 est conjugé à/à la FL594

Application: Immunocytochemistry (ICC)

Clone: N128A-2

Détail du produit anti-GSG2 anticorps (FL594)

Épitope: AA 1-798

Fonction: Anti-Haspin/GSG2 Antibody FL594 Conjugate

Specificité: No off-targets reported

Réactivité croisée: Humain

Attributs du produit:

Description: Our Anti-Haspin/GSG2 mouse monoclonal primary antibody is produced in-house from hybridoma clone N128A/2. It detects human Haspin/GSG2, and is purified by Protein A chromatography. It is great for use in ICC.

Manufacturer Comment: We produce our Haspin/GSG2 mouse monoclonal primary antibody from hybridoma clone N128A/2. It is great in ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Pureté: > 90 % specific antibody

Immunogène: Fusion protein amino acids 1-798 (full-length) of human Haspin (accession number Q8TF76)

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Date de péremption: 12 months

Détails sur GSG2

Antigène: GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

Autre désignation: GSG2

Sujet:

Synonyms: Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein) (H-haspin) (Haploid germ cell-specific nuclear protein kinase)

Target Description: Histone H3 Associated Protein Kinase is encoded by the gene HASPIN. HASPIN is a member of the protein kinase superfamily, Ser/Thr protein kinase family, and the Haspin subfamily. HASPIN is a serine/threonine - protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. HASPIN may act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment, and normal progression through the cell cycle. HASPIN is expressed in the testis, thymus, bone marrow, prostate, intestine, lung, spleen, and lymph node. No diseases were found to be associated with HASPIN.

Gene Name Alternatives: HASPIN GSG2

Poids moléculaire: 90 kDa