CNTNAP2 anticorps (Extracellular Domain) (FL594)

N° du produit ABIN7595780

Cet anticorps Souris Monoclonal détecte spécifiquement CNTNAP2 dans IHC et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour CNTNAP2 anticorps (Extracellular Domain) (FL594) (ABIN7595780)

Antigène: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CNTNAP2 est conjugé à/à la FL594

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: K67-25

Détail du produit anti-CNTNAP2 anticorps (FL594)

Épitope: Extracellular Domain

Fonction: Anti-CASPR2 Antibody FL594 Conjugate

Specificité: No off-targets reported for Caspr/paranodin

Réactivité croisée: Humain, Souris, Rat

Attributs du produit:

Description: Our Anti-CASPR2 mouse monoclonal primary antibody is produced in-house from hybridoma clone K67/25. It is KO validated, detects human, mouse, and rat CASPR2, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our CASPR2 mouse monoclonal primary antibody from hybridoma clone K67/25. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Pureté: > 90 % specific antibody

Immunogène: Fusion protein 96-1265 (extracellular domain) of human Caspr2 (accession number A0A090N7T7) produced recombinantly in E. Coli

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Date de péremption: 12 months

Détails sur CNTNAP2

Antigène: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Autre désignation: CASPR2

Sujet:

Synonyms: Contactin associated protein-like 2 (Contactin associated protein-like 2, isoform CRA_b)

Target Description: Contactin-associated protein-like 2 protein, or Caspr2, is a neuronal transmembrane member of the Neurexin family. Structural features of Caspr2 include epidermal growth factor repeats, laminin G domains, F5/8 type C domain, fibrinogen-like domains, and PDZ binding sites. Caspr2 is a cell adhesion molecule as well as a receptor. It is involved in mediating cell-cell interactions in the nervous system and involved in neural-glia interactions and clustering of potassium channels in myelinated axons. It is expressed at the juxaperanodal region of nodes of Ranvier in the CNS and PNS. Changes in expression have been associated with increased susceptibility to autism and epilepsy.

Gene Name Alternatives: CNTNAP2 hCG_15499 tcag7.496

Poids moléculaire: 180 kDa