DLG2 anticorps (AA 1-852) (FL650)

N° du produit ABIN7595813

Cet anticorps Souris Monoclonal détecte spécifiquement DLG2 dans IHC et ICC. Il présente une réactivité envers Rat.

Aperçu rapide pour DLG2 anticorps (AA 1-852) (FL650) (ABIN7595813)

Antigène: DLG2 (Discs, Large Homolog 2 (DLG2))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DLG2 est conjugé à/à la FL650

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N18-30

Détail du produit anti-DLG2 anticorps (FL650)

Épitope: AA 1-852

Fonction: Anti-Chapsyn-110/PSD-93 Antibody FL650 Conjugate

Specificité: No off-targets reported for other MAGUK family members PSD-95, SAP97, SAP102 expressed in transfected cells

Réactivité croisée: Humain, Souris, Lapin, Rat

Attributs du produit:

Description: Our Anti-Chapsyn-110/PSD-93 mouse monoclonal primary antibody is produced in-house from hybridoma clone N18/30. It is KO validated, detects human, mouse, rabbit, and rat Chapsyn-110/PSD-93, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our Chapsyn-110/PSD-93 mouse monoclonal primary antibody from hybridoma clone N18/30. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Pureté: > 90 % specific antibody

Immunogène: Fusion protein amino acids 1-852 of rat Chapsyn-110 (accession number Q63622) produced recombinantly in E. Coli

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Date de péremption: 12 months

Détails sur DLG2

Antigène: DLG2 (Discs, Large Homolog 2 (DLG2))

Autre désignation: PSD-93

Sujet:

Synonyms: Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)

Target Description: PSD-93/Chapsyn-110 (also known as Channel-associated protein of synapse-110, Postsynaptic density protein PSD-93, Disks large homolog 2 and Dlg2) is a member of the membrane-associated guanylate kinase (MAGUK) family. The protein contains a guanylate kinase-like domain, 3 PDZ domains and 1 SH3 domain. Chapsyn110 binds to NMDA receptor subunits and Shaker K+ channel subunits to aid in forming a multiprotein scaffold which clusters receptors, ion channels, cytoskeletal protiens and other cell signaling proteins. In this manner, it plays a key role in postsynaptic targeting. It is found in brain in neuronal cells and located at the cell synapse, postsynaptic cell membrane and postsynaptic density. Chapsyn110 has been implicated in chronic pain, bilateral retinoblastoma and schizophrenia.

Gene Name Alternatives: Dlg2 Dlgh2

Poids moléculaire: 110 kDa