LSM2 anticorps (AA 1-95)

N° du produit ABIN7596084

Cet anticorps Souris Monoclonal détecte spécifiquement LSM2 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour LSM2 anticorps (AA 1-95) (ABIN7596084)

Antigène: LSM2 (LSM2 Homolog, U6 Small Nuclear RNA Associated (LSM2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LSM2 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: AT1G7

Détail du produit anti-LSM2 anticorps

Épitope: AA 1-95

Fonction: Human LSM2 antibody

Purification: Purified

Immunogène: Recombinant human LSm2 (1-95aa) purified from E. coli

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détails sur LSM2

Antigène: LSM2 (LSM2 Homolog, U6 Small Nuclear RNA Associated (LSM2))

Autre désignation: LSM2

Sujet: LSM2 is a member of the LSm family of RNA-binding proteins. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner. Component of the cytoplasmic complex which is thought to be involved in mRNA degradation by activating the decapping step. Component of the nuclear LSM2 complex, which is involved in splicing of nuclear mRNAs. LSM2 associates with multiple snRNP complexes containing the U6 snRNA It binds directly to the U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. It probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping. LSM2 binds specifically to the 3'-terminal U-tract of U6 snRNA. LSM2-LSM8 probably is involved in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.

NCBI Accession: NP_067000

Pathways: Ribonucleoprotein Complex Subunit Organization