Cet anticorps anti-ACAT1 Monoclonal Souris (Clone 2C5) (ABIN7596086) détecte spécifiquement ACAT1 dans WB, ELISA, IF et ICC.
L’anticorps est réactif avec des échantillons de Humain.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Antigène
ACAT1
(Acetyl-CoA Acetyltransferase 1 (ACAT1))
Autre désignation
ACAT1
Sujet
ACAT1 (acetyl-Coenzyme A acetyltransferase 1) is a 417 amino acid protein. ACAT1 is a mitochondrial enzyme involved in the formation and degradation of ketone bodies and is necessary for the proper metabolic processing of isoleucine. ACAT1 and ACAT2 catalyze the formation of acetoacetyl-CoA from two acetyl-CoA molecules. These enzymes are also capable of the reverse reaction. Defects in ACAT1 are a cause of 3-ketothiolase deficiency. 3-ketothiolase deficiency is an inborn error of isoleucine catabolism characterized by intermittent ketoacidotic attacks associated with unconsciousness. Some patients die during an attack or are mentally retarded.