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PRPS1 anticorps (AA 1-318)

Cet anticorps anti-PRPS1 est un anticorps Souris Monoclonal détectant PRPS1 dans WB, ELISA, IF et ICC. Adapté pour Humain.
N° du produit ABIN7596089

Aperçu rapide pour PRPS1 anticorps (AA 1-318) (ABIN7596089)

Antigène

Voir toutes PRPS1 Anticorps
PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))

Reactivité

  • 8
  • 2
  • 1
Humain

Hôte

  • 5
  • 3
Souris

Clonalité

  • 6
  • 2
Monoclonal

Conjugué

  • 8
Cet anticorp PRPS1 est non-conjugé

Application

  • 8
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone

AT1E11
  • Épitope

    • 3
    • 2
    • 1
    AA 1-318

    Fonction

    Human PRPS1 antibody

    Purification

    protein-A affinity chromatography

    Immunogène

    Recombinant human PRPS1 (1-318aa) purified from E. coli

    Isotype

    IgG2a kappa
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C,-80 °C

    Stockage commentaire

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • Antigène

    PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))

    Autre désignation

    PRPS1

    Sujet

    PRPS1 is an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. A mutation in PRPS1 may result in PRPS superactivity, a disease characterized by gout and the overproductionof purine nucleotides, uric acid and PRPP. PRPS1 mutations can also lead to a reduction in PRPS1 activity resulting in ARTS syndrome or CMTX5 (Charcot-Marie-Tooth disease X-linked recessive type 5).

    NCBI Accession

    NP_002755

    Pathways

    Ribonucleoside Biosynthetic Process
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