SPA17 anticorps (AA 1-136)
Aperçu rapide pour SPA17 anticorps (AA 1-136) (ABIN7598987)
Antigène
Voir toutes SPA17 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-136
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Fonction
- Anti-SPA17 Antibody
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Réactivité croisée (Details)
- No cross reactivity with other proteins.
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Homologie
- Human SPA17 shares 75.7% amino acid (aa) sequence identity with mouse SPA17.
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Attributs du produit
- Anti-SPA17 Antibody. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human SPA17 recombinant protein (Position: M1-K136). Human SPA17 shares 75.7% amino acid (aa) sequence identity with mouse SPA17.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- SPA17 (Sperm Autoantigenic Protein 17 (SPA17))
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Autre désignation
- SPA17
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Sujet
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Background: Sperm surface protein Sp17 is a protein that in humans is encoded by the SPA17 gene. This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.
Gene Full Name: sperm autoantigenic protein 17
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Poids moléculaire
- 22 kDa
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ID gène
- 53340
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UniProt
- Q15506
Antigène
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