SSBP1 anticorps (AA 1-148)

N° du produit ABIN7599002

Cet anticorps anti-SSBP1 est un anticorps Lapin Polyclonal détectant SSBP1 dans WB, ELISA, IHC, IF, ICC et FACS. Adapté pour Humain.

Aperçu rapide pour SSBP1 anticorps (AA 1-148) (ABIN7599002)

Antigène: SSBP1 (Single-Stranded DNA Binding Protein 1 (SSBP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SSBP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-SSBP1 anticorps

Épitope: AA 1-148

Fonction: Anti-SSBP1 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-SSBP1 Antibody Picoband® (ABIN7599002). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SSBP1 recombinant protein (Position: M1-E148).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.25 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 1-2 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bogenhagen, D. F., Rousseau, D., Burke, S. The layered structure of human mitochondrial DNA nucleoids. J. Biol. Chem. 283: 3665-3675, 2008. 2. Del Dotto, V., Ullah, F., Di Meo, I., Magini, P., Gusic, M., Maresca, A., Caporali, L., Palombo, F., Tagliavini, F., Baugh, E. H., Macao, B., Szilagyi, Z., and 35 others. SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder. J. Clin. Invest. 130: 108-125, 2020. 3. Huang, J., Gong, Z., Ghosal, G., Chen, J. SOSS complexes participate in the maintenance of genomic stability. Molec. Cell 35: 384-393, 2009.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur SSBP1

Antigène: SSBP1 (Single-Stranded DNA Binding Protein 1 (SSBP1))

Autre désignation: SSBP1

Sujet:

Synonyms: Protein Dok-7, Downstream of tyrosine kinase 7, DOK7, C4orf25,

Tissue Specificity: Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen .

Background: Single-stranded DNA-binding protein, mitochondrial is a protein that in humans is encoded by the SSBP1 gene. SSBP1 is a housekeeping gene involved in mitochondrial biogenesis. It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability.

Poids moléculaire: 16 kDa

ID gène: 6742

UniProt: Q04837

Pathways: Chromatin Binding