TSR2 anticorps (AA 1-176)

N° du produit ABIN7599035

L’anticorps Lapin Polyclonal anti-TSR2 a été validé pour ELISA, WB et IHC. Il convient pour détecter TSR2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TSR2 anticorps (AA 1-176) (ABIN7599035)

Antigène: TSR2 (TSR2, 20S rRNA Accumulation, Homolog (TSR2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSR2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TSR2 anticorps

Épitope: AA 1-176

Fonction: Anti-TSR2 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-TSR2 Antibody Picoband® (ABIN7599035). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TSR2 recombinant protein (Position: M1-E176).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Gripp, K. W., Curry, C., Olney, A. H., Sandoval, C., Fisher, J., Chong, J. X.-L., UW Center for Mendelian Genomics, Pilchman, L., Sahraoui, R., Stabley, D. L., Sol-Church, K. Diamond-Blackfan anemia with mandibulofacial dystostosis (sic) is heterogeneous, including the novel DBA genes TSR2 and RPS28. Am. J. Med. Genet. 164A: 2240-2249, 2014. 2. Gripp, K. W., McDonald-McGinn, D. M., La Rossa, D., McGain, D., Federman, N., Vlachos, A., Glader, B. E., McKenzie, S. E., Lipton, J. M., Zackai, E. H. Bilateral microtia and cleft palate in cousins with Diamond-Blackfan anemia. Am. J. Med. Genet. 101: 268-274, 2001. 3. He, H., Zhu, D., Sun, J., Pei, R., Jia, S. The novel protein TSR2 inhibits the transcriptional activity of nuclear factor-kappa-B and induces apoptosis. Molec. Biol. (Mosk) 45: 451-457, 2011.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur TSR2

Antigène: TSR2 (TSR2, 20S rRNA Accumulation, Homolog (TSR2))

Autre désignation: TSR2

Sujet:

Synonyms: Mitochondrial import inner membrane translocase subunit Tim17-A, Inner membrane preprotein translocase Tim17a, TIMM17A, MIMT17, TIM17, TIM17A, TIMM17

Background: TSR2 ribosome maturation factor is a protein that in humans is encoded by the TSR2 gene. The protein encoded by this gene appears to repress the transcription of NF-kappaB and may be involved in apoptosis. Defects in this gene are a cause of Diamond-Blackfan anemia.

Poids moléculaire: 24-30 kDa

ID gène: 90121

UniProt: Q969E8