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ISOC2 anticorps (AA 1-205)

L’anticorps Lapin Polyclonal anti-ISOC2 a été validé pour WB, ELISA, ICC et IF. Il convient pour détecter ISOC2 dans des échantillons de Humain, Souris et Rat.
N° du produit ABIN7599080

Aperçu rapide pour ISOC2 anticorps (AA 1-205) (ABIN7599080)

Antigène

Voir toutes ISOC2 Anticorps
ISOC2 (Isochorismatase Domain Containing 2 (ISOC2))

Reactivité

Humain, Souris, Rat

Hôte

  • 14
  • 2
Lapin

Clonalité

  • 15
Polyclonal

Conjugué

  • 11
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ISOC2 est non-conjugé

Application

Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Épitope

    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-205

    Fonction

    Anti-ISOC2 Antibody Picoband®

    Attributs du produit

    Anti-ISOC2 Antibody Picoband® (ABIN7599080). Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived human ISOC2 recombinant protein (Position: M1-H205). Human ISOC2 shares 84.2% and 75% amino acid (aa) sequence identity with mouse and rat ISOC2, respectively.
  • Indications d'application

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Huang, X., Shi, Z., Wang, W., Bai, J., Chen, Z., Xu, J., Zhang, D., Fu, S. Identification and characterization of a novel protein ISOC2 that interacts with p16(INK4a). Biochem. Biophys. Res. Commun. 361: 287-293, 2007.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Antigène

    ISOC2 (Isochorismatase Domain Containing 2 (ISOC2))

    Autre désignation

    ISOC2

    Sujet

    ISOC2 (isochorismatase domain-containing protein 2) is a 205 amino acid protein belonging to the isochorismatase family. Isochorismatase is an enzyme that catalyzes the chemical reaction of isochorismate and water to 2,3-dihydroxy-2,3-dihydrobenzoate and pyruvate. Localized to mitochondrion and cytoplasm, ISOC2 interacts with CDKN2A and localizes to the nucleus in the presence of it. ISOC2 is ubiquitously expressed, with highest levels found in uterus, stomach and urinary tract system. Over-expressed ISOC2 inhibits the expression of CDKN2A, suggesting that this novel gene may play a role during tumor development by interacting with CDKN2A. Three isoforms are produced by alternative splicing events.

    Poids moléculaire

    22 kDa

    ID gène

    79763
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